A Student Perspective on the 18th Monitoring Molecules in Neuroscience Meeting in Lyon.

After being postponed twice due to the global COVID-19 pandemic, approximately 200 scientists gathered in Lyon, France, in late June 2022 for the 18th Biennial Monitoring Molecules in Neuroscience (MMiN) Research Conference. Although there were unprecedented challenges involved with coordinating the 18th MMiN conference, the meeting was a huge success. The meeting provided a wonderful opportunity for young neuroscientists to network and learn about the current state of molecular monitoring in neuroscience research. The topics spanned advancements in well-established analytical techniques to novel method development. Some of the noteworthy techniques expediting our understanding of circuit-level neurochemical function include multiplexed detection of numerous neurochemicals, well-established sensors leveraging enzymes and other biologic components, and the development of diverse, customizable genetically encoded sensors.

Use of mental health services in the aftermath of COVID-19 waves: a retrospective study conducted in a French Psychiatric and Neurosciences University Hospital.

OBJECTIVE: The COVID-19 pandemic and the restrictive measures taken to prevent its propagation had profound effects on mental health and well-being, especially in children and young adults (<25 years old). This study aimed to analyse the medium and long-term impact of the COVID-19 pandemic on the use of the mental health services, by age groups and gender. DESIGN: We conducted a retrospective study using the medical and administrative information system databases of patients, between 2019 and 2021. SETTING: This study was conducted in the Groupe Hospitalier Universitaire Paris Psychiatry and Neurosciences. OUTCOME MEASURES: We reported three indicators: the number of new patients attending outpatient clinics, the number of emergency department (ED) visits and the number of hospital admissions. METHODS: We considered the weekly number of each indicator, by age groups and by gender. We also collected the reasons of ED visits and hospital admissions. The 2020 and 2021 data were compared with the same period in 2019. The evolution of the indicators over the 3 years was analysed with interrupted time-series analysis. RESULTS: All three indicators showed a dramatic decrease during the first lockdown period (March 2020) especially for the youngest. In 2021, the activity resumed but without reaching its prepandemic level. Moreover, mental healthcare seeking was significantly lower since the beginning of the pandemic compared with the prepandemic period for all age groups, except for young women (<25 years old). Among them, there was a higher level of mental health services use in 2021, compared with 2019: +20% of new patients at the outpatient clinics, +39% of ED visits and+17% of hospital admissions. CONCLUSIONS: The COVID-19 pandemic has had severe consequences on populations' mental health, especially among young women, which seem to persist months after the end of restrictive measures.

The Analyst's Self-Care: Further Reflections after the Pandemic on Cultivating Resilience and the Essential Role of the Body-Mind Relationship in Clinical Practice.

Sparse attention is paid in the psychoanalytic literature to the management of self-care needs of the analyst. I suggest that pandemic fatigue experienced by psychotherapists during the Covid-19 global crisis has thrown into bold relief the requirement for clinicians to attune to the body, particularly the requirement for rest and creative space. Physical and emotional exhaustion is multidetermined and not unique to this time period; the global crisis appears to have unmasked particular difficulties in sensing and tending to requirements of the body-mind. Changes observed in sleep, dreams, exercise, eating, and somatic states during the pandemic raise additional questions about modifiable risk factors of burnout. Drawing upon contemporary evidence emerging from the fields of cognitive psychology, neuroscience, and psychodynamic practice and theory, suggestions are made to assist the analyst in rendering essential self-care.

Collaborating neuroscience online: The case of the Human Brain Project forum.

This paper analyzes user interactions on the public-access online forum of the Human Brain Project (HBP), a major European Union-funded neuroscience research initiative, to understand the utility of the Forum for collaborative problem solving. We construct novel data using discussion forum posts and detailed user profiles on the HBP Forum. We find that HBP Forum utilization is comparable to that of a leading general-interest coding platform, and that online usage metrics quickly recovered after an initial Covid-19-related dip. Regression results show that user interactions on the Forum are more active for questions on programming and in HBP core areas. Further, Cox proportional hazard analyses show that such problems are solved faster. Forum posts with users from different countries tend to be discussed more actively but solved slower. Higher shares of administrator support tend to solve problems faster. There are no clear patterns regarding gender and seniority. Our results suggest that building novel collaborative forums can support researchers working on complex topics in challenging times.

Diversity in neuroscience education: A perspective from a Historically Black institution.

The events of 2020, including the pandemic which highlighted the extent of health disparities in the United States, combined with the Black Lives Matter protests, have focused public attention on the systemic inequities that continue to afflict our nation. Publicly available data from the National Center for Education Statistics show that our discipline of neuroscience shows the same types of disparities, particularly for African-American students. I have drawn on data from the Integrated Postsecondary Education Data Survey of U.S. colleges and universities to show that while the number of graduates from neuroscience undergraduate and graduate degree programs has grown dramatically in this century, only a small percentage of those graduates are African American, and the numbers are growing very slowly. I also present data on the neuroscience PhD program at my institution, Delaware State University, the only Historically Black University in the United States to offer a PhD in neuroscience. Because a high percentage of our students and graduates are African American, our small, young program has the potential for great impact in diversifying our discipline of neuroscience. While elite colleges and research-intensive universities have been engaged for decades in efforts to increase diversity in their academic programs, change is slow, and large inequities remain. With Delaware State University's neuroscience PhD program as an example, I hope to convince readers that it is time for our nation to recognize the institutions that are best positioned to serve students from communities of color, and direct resources to support their growth and success.

Early experience unpredictability in child development as a model for understanding the impact of the COVID-19 pandemic: A translational neuroscience perspective.

Extensive evidence links adverse experiences during childhood to a wide range of negative consequences in biological, socioemotional, and cognitive development. Unpredictability is a core element underlying most forms of early adversity; it has been a focus of developmental research for many years and has been receiving increasing attention recently. In this article, we propose a conceptual model to describe how unpredictable and adverse early experiences affect children's neurobiological, behavioral, and psychological development in the context of the COVID-19 pandemic. We first highlight the critical role of unpredictability in child development by reviewing existing conceptual models of early adversity as they relate to subsequent development across the lifespan. Then, we employ a translational neuroscience framework to summarize the current animal- and human-based evidence on the neurobiological alterations induced by early experience unpredictability. We further argue that the COVID-19 pandemic serves as a global "natural experiment" that provides rare insight to the investigation of the negative developmental consequences of widespread, clustered, and unpredictable adverse events among children. We discuss how the pandemic helps advance the science of unpredictable early adverse experiences. As unpredictability research continues to grow, we highlight several directions for future studies and implications for policymaking and intervention practices.

Kay M. Tye.

Kay M. Tye shares how focusing on personal and team mental and physical health forms the necessary foundation for future success. In an interview with Neuron, she also discusses the need for better representation in STEM and how global lockdowns have reinvigorated her scientific interests in social homeostasis.

Gregory Quirk.

Gregory Quirk has worked in New York, Honduras, and Puerto Rico with a decades-long commitment to mentorship and the global promotion of neuroscience. In an interview with Neuron, he talks about his upcoming move to the University of the Philippines and how virtual meetings are making us rethink collaborations and interactions with members of the community.

Eunji Cheong.

In Korea, the pandemic has elevated scientists as trusted sources for both policy decisions and dinner table conversation. In an interview with Neuron, Eunji Cheong discusses how we need to support future generations by fostering scientific thinking, patience, and flexibility.

Ishmail Abdus-Saboor.

In an interview with Neuron, Ishmail Abdus-Saboor talks about the future of team science and how the pandemic has renewed faith in basic research, and he emphasizes the importance of humanity and diversity in science for fueling innovation and equal talent needing equal opportunity.

Xiang Yu.

In this Neuron Q&A, Xiang Yu talks about the stress and anxiety brought to the lab by the pandemic, the new opportunities for teaching and scientific conferences it created, the value of the individual, and the social responsibility of science for humanity and society to shape a brighter future.

For love of neuroscience: The Neuromatch movement.

In this meeting report, I applaud the Neuromatch community, which runs virtual summer schools and conferences in response to the pandemic. Its members love science, aim to advance our understanding of the brain, and work extremely hard to include everyone.

Greg Stuart.

In an interview with Neuron, Greg Stuart discusses the COVID-19 pandemic effects on the Australian research landscape and recounts how early influencers shaped him as both a neuroscientist and mentor.

Shubha Tole.

Shubha Tole, Dean of Graduate Studies at the Tata Institute of Fundamental Research in Mumbai, India, shares with Neuron her approach to mentorship during these challenging times, how connecting diverse perspectives across the globe makes us stronger, and her love of the arts-including classical dance and poetry.